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Single Molecule Conductance of DNA Bases and Sequencing by Tunneling; Imaging Nucleic Acids with the AFM

carpick — Sat, 22 Aug 2009 15:05:56 +0000

From: Agilent Technologies’ AFM University Website.

Single Molecule Conductance of DNA Bases and Sequencing by Tunneling; Imaging Nucleic Acids with the AFM
Running time: 56 minutes
April 8, 2009
Speakers: Stuart Lindsay, PhD Arizona State University, Edward and Nadine Carson Professor of Physics and Chemistry Biodesign Institute; W. Travis Johnson, PhD, Research Scientists, Agilent Technologies

Single Molecule Conductance of DNA Bases and Sequencing by Tunneling.
The scanning probe microscope is a great tool for measuring the conductance of single molecules. Tunneling current measurements are sensitive to the hydrogen bonding between base-pairs, while measurements of the conductance of base-nucleoside pairs yields a value for their absolute conductance, opening the way to design of a device that sequences DNA by means of tunneling measurements.

“Imaging Nucleic Acids with the AFM”
Atomic Force Microscopy (AFM) can be used to obtain highly accurate, nanometer scale images of nucleic acids, including DNA and RNA, in air or in physiological conditions. This makes the AFM a powerful analytical tool to study the structure and function of DNA. In this seminar the study of nucleic acids via AFM will be discussed and explored.

Image Contest – Early Entries

NN Admin — Wed, 29 Jul 2009 21:38:54 +0000

Below are the first set of entries to the Nanoprobe Network’s Image Contest. The person submitting the best image will win an iPod Nano!

Enter by July 31. Contest submission instructions are here

Azobenzne Assembly

Ajeet Kumar

Penn State University

STM 3D-Image of 1,4-diisocyanobenzene SAMs

Florencia Calaza

University of Wisconsin-Milwaukee

Red Blood Cells

Peter Eaton

REQUIMTE/University of Porto,Â Portugal

Stem Cell Cytoskeleton Fluo AFM

Andre Brown

University of Cambridge

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This STM image shows a high coverage of dibutyl sulfide on a Au surface. The individual molecules can be seen to form rows which flow over the underlying herringbone stripes from the surface.

Heather Tierney

Tuft University

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The scan shows multiple fragments of 30 mer poly-T ssDNA wrapped around a swCNT. The substrate material is Mica

Husein Rokadia

University of Arkansas

Nanoscale Video Lectures from Winter Quarter 2007

Altitude Marketing — Tue, 05 May 2009 18:15:44 +0000

Course Overview	Malcolm Beasley	1/10/07	http://www.stanford.edu/group/cpn/education/070110BeasleyIntro.htm
Imaging Introduction	Kathryn Moler	1/10/07	http://www.stanford.edu/group/cpn/education/0110Moler.htm
Introduction to Atomic Force Microscopy	Dan Rugar	1/12/07	http://www.stanford.edu/group/cpn/education/0112Rugar.htm
Mechanics of AFM Cantilevers	Adrian Lew	1/17/07	http://www.stanford.edu/group/cpn/education/0117Lew
AFM Modes and Fabrication	Olav Solgaard	1/19/07	http://www.stanford.edu/group/cpn/education/0119Solg.htm
Introduction to STM	Malcolm Beasely	1/24/07	http://www.stanford.edu/group/cpn/education/0124Beas.htm
Theory of Scanning Tunneling Microscopy	Barbara Jones	1/26/07	http://www.stanford.edu/group/cpn/education/0126Jones.htm
Scanning Potentiometry	Malcolm Beasley	1/29/07	http://www.stanford.edu/group/cpn/education/0129Beas.htm
Scanning Gate Microscopy	David Goldhaber-Gordon	1/31/07	http://www.stanford.edu/group/cpn/education/0131DGG.htm
Basics of Scanning Near-field Optical Microscopy	Mark Brongersma	2/5/07	http://www.stanford.edu/group/cpn/education/0205Bron.htm
Scanning Microwave Microscopy	Mike Kelly	2/7/07	http://www.stanford.edu/group/cpn/education/070207Kelly.htm
Hall Probes and Magnetic Force Microscopy	Kathryn Moler	2/12/07	http://www.stanford.edu/group/cpn/education/070221Moler.htm
Scanning SQUID Microscopy	John Kirtley	2/14/07	http://www.stanford.edu/group/cpn/education/070214Kirtley.htm
SNOM: Applications and Opportunities	Mark Brongersma	2/28/07	http://www.stanford.edu/group/cpn/education/070228Bron.htm

Nanoscale Video Lectures from Winter Quarter 2006

Altitude Marketing — Tue, 05 May 2009 18:07:51 +0000

CPN Introduction	Kathryn Moler	1/11/06	http://www.stanford.edu/group/cpn/education/kammoler011106.htm
Theory of Scanning Tunneling Microscopy	Barbara Jones	1/18/06	http://www.stanford.edu/group/cpn/education/060118Jones.htm
Scanning Potentiometry	Malcolm Beasley	1/20/06	http://www.stanford.edu/group/cpn/education/060120Beasley.htm
Scanning Gate Microscopy	David Goldhaber-Gordon	1/23/06	http://www.stanford.edu/group/cpn/education/060123DGG.htm
Principles of Atomic Force Microscopy	Dan Rugar	1/25/06	http://www.stanford.edu/group/cpn/education/060125Rugar.htm
AFM Cantilever Fabrication	Olav Solgaard	2/1/06	http://www.stanford.edu/group/cpn/education/060201Solgaard.htm
Scanning SQUID Microscopy	John Kirtley	2/8/06	http://www.stanford.edu/group/cpn/education/kirtley060208.htm
Scanning Near-Field Optical Microscopy	Mark Brongersma	2/13/06	http://www.stanford.edu/group/cpn/education/060213Brongersma.htm
Hall Probes and Magnetic Force Microscopy	Kathryn Moler	3/13/06	http://www.stanford.edu/group/cpn/education/060210moler.htm

Nanotechnology Fighting Cancer

NN Admin — Thu, 02 Apr 2009 18:51:41 +0000

Nanotechnology’s Role in Fighting Cancer

One of the predominant features of nano-materials is an extremely high surface area. In this episode, Chris Landry, professor of chemistry at the University of Vermont describes how nanotechnology applications are improving the efficacy of cancer drugs by delivering more medicine to patients.

FightingCancer

For more information, please visit: http://www.vpt.org/programs/emergingscience_videopodcas.html